PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT3G50870.1
Common NameF18B3.150, GATA18, HAN, MNP
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family GATA
Protein Properties Length: 295aa    MW: 31831.5 Da    PI: 8.0055
Description GATA family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT3G50870.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1GATA63.23e-20154188135
         GATA   1 CsnCgttkTplWRrgpdgnktLCnaCGlyyrkkgl 35 
                  C+nC tt+TplWR+gp+g+k+LCnaCG++++k+++
  AT3G50870.1 154 CANCDTTSTPLWRNGPRGPKSLCNACGIRFKKEER 188
                  ********************************986 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM004013.2E-19148200IPR000679Zinc finger, GATA-type
PROSITE profilePS5011413.943148184IPR000679Zinc finger, GATA-type
SuperFamilySSF577161.62E-13151191No hitNo description
Gene3DG3DSA:3.30.50.101.2E-16152188IPR013088Zinc finger, NHR/GATA-type
CDDcd002021.24E-12153185No hitNo description
PfamPF003207.2E-18154188IPR000679Zinc finger, GATA-type
PROSITE patternPS003440154179IPR000679Zinc finger, GATA-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009793Biological Processembryo development ending in seed dormancy
GO:0009909Biological Processregulation of flower development
GO:0030154Biological Processcell differentiation
GO:0045944Biological Processpositive regulation of transcription from RNA polymerase II promoter
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0000977Molecular FunctionRNA polymerase II regulatory region sequence-specific DNA binding
GO:0001085Molecular FunctionRNA polymerase II transcription factor binding
GO:0001228Molecular Functiontranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0003682Molecular Functionchromatin binding
GO:0008270Molecular Functionzinc ion binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0009005anatomyroot
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009052anatomyflower pedicel
PO:0025022anatomycollective leaf structure
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 295 aa     Download sequence    Send to blast
MMQTPYTTST QGQYCHSCGM FHHHSQSCCY NNNNNSNAGS YSMVFSMQNG GVFEQNGEDY  60
HHSSSLVDCT LSLGTPSTRL CEEDEKRRRS TSSGASSCIS NFWDLIHTKN NNSKTAPYNN  120
VPSFSANKPS RGCSGGGGGG GGGGGGDSLL ARRCANCDTT STPLWRNGPR GPKSLCNACG  180
IRFKKEERRT TAATGNTVVG AAPVQTDQYG HHNSGYNNYH AATNNNNNNG TPWAHHHSTQ  240
RVPCNYPANE IRFMDDYGSG VANNVESDGA HGGVPFLSWR LNVADRASLV HDFTR
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.277610.0bud| flower
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306933670.0
Genevisible252128_at0.0
Expression AtlasAT3G50870-
AtGenExpressAT3G50870-
ATTED-IIAT3G50870-
Functional Description ? help Back to Top
Source Description
TAIREncodes a GATA factort transcriptional regulator required to position the proembryo boundary in the early embryo.
UniProtTranscriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. {ECO:0000250}.
Function -- GeneRIF ? help Back to Top
  1. Mutations in HAN cause a coordinated apical shift of gene expression patterns, revealing that HAN regulates transcription in the basal proembryo.
    [PMID: 20643354]
  2. The data suggested that establishing cotyledon identity requires both GIF1 and HANABA TARANU to repress ectopic root formation by repressing PLETHORA1 expression.
    [PMID: 22669825]
  3. HAN functions as a key repressor that regulates floral development via regulatory networks involving genes in the GATA3 family, along with genes involved in hormone action and floral organ specification.
    [PMID: 23335616]
  4. HAN physically interacts with JAG, and directly stimulates the expression of JAG and BOP2 to regulate floral organ development
    [PMID: 26390296]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT3G50870.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
BioGRIDAT3G50870
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT3G50870
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB4936440.0AB493644.1 Arabidopsis thaliana At3g50870 mRNA for hypothetical protein, partial cds, clone: RAAt3g50870.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_566939.10.0GATA transcription factor 18
SwissprotQ8LC790.0GAT18_ARATH; GATA transcription factor 18
TrEMBLC0SVE10.0C0SVE1_ARATH; Putative uncharacterized protein At3g50870 (Fragment)
STRINGAT3G50870.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM40572556
Representative plantOGRP6817287
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Jeong MJ,Jeong MJ,Shih MC
    Interaction of a GATA factor with cis-acting elements involved in light regulation of nuclear genes encoding chloroplast glyceraldehyde-3-phosphate dehydrogenase in Arabidopsis.
    Biochem. Biophys. Res. Commun., 2003. 300(2): p. 555-62
    [PMID:12504119]
  3. Reyes JC,Muro-Pastor MI,Florencio FJ
    The GATA family of transcription factors in Arabidopsis and rice.
    Plant Physiol., 2004. 134(4): p. 1718-32
    [PMID:15084732]
  4. Zhao Y, et al.
    HANABA TARANU is a GATA transcription factor that regulates shoot apical meristem and flower development in Arabidopsis.
    Plant Cell, 2004. 16(10): p. 2586-600
    [PMID:15367721]
  5. Nawy T, et al.
    Transcriptional profile of the Arabidopsis root quiescent center.
    Plant Cell, 2005. 17(7): p. 1908-25
    [PMID:15937229]
  6. Nakayama N, et al.
    Gene trap lines define domains of gene regulation in Arabidopsis petals and stamens.
    Plant Cell, 2005. 17(9): p. 2486-506
    [PMID:16055634]
  7. Bi YM, et al.
    Genetic analysis of Arabidopsis GATA transcription factor gene family reveals a nitrate-inducible member important for chlorophyll synthesis and glucose sensitivity.
    Plant J., 2005. 44(4): p. 680-92
    [PMID:16262716]
  8. Manfield IW,Devlin PF,Jen CH,Westhead DR,Gilmartin PM
    Conservation, convergence, and divergence of light-responsive, circadian-regulated, and tissue-specific expression patterns during evolution of the Arabidopsis GATA gene family.
    Plant Physiol., 2007. 143(2): p. 941-58
    [PMID:17208962]
  9. Stracke R, et al.
    Differential regulation of closely related R2R3-MYB transcription factors controls flavonol accumulation in different parts of the Arabidopsis thaliana seedling.
    Plant J., 2007. 50(4): p. 660-77
    [PMID:17419845]
  10. Ho LH, et al.
    Identification of regulatory pathways controlling gene expression of stress-responsive mitochondrial proteins in Arabidopsis.
    Plant Physiol., 2008. 147(4): p. 1858-73
    [PMID:18567827]
  11. Whipple CJ, et al.
    A conserved mechanism of bract suppression in the grass family.
    Plant Cell, 2010. 22(3): p. 565-78
    [PMID:20305121]
  12. Nawy T, et al.
    The GATA factor HANABA TARANU is required to position the proembryo boundary in the early Arabidopsis embryo.
    Dev. Cell, 2010. 19(1): p. 103-13
    [PMID:20643354]
  13. Causier B,Ashworth M,Guo W,Davies B
    The TOPLESS interactome: a framework for gene repression in Arabidopsis.
    Plant Physiol., 2012. 158(1): p. 423-38
    [PMID:22065421]
  14. Kanei M,Horiguchi G,Tsukaya H
    Stable establishment of cotyledon identity during embryogenesis in Arabidopsis by ANGUSTIFOLIA3 and HANABA TARANU.
    Development, 2012. 139(13): p. 2436-46
    [PMID:22669825]
  15. Zhang X, et al.
    Transcription repressor HANABA TARANU controls flower development by integrating the actions of multiple hormones, floral organ specification genes, and GATA3 family genes in Arabidopsis.
    Plant Cell, 2013. 25(1): p. 83-101
    [PMID:23335616]
  16. Ding L, et al.
    HANABA TARANU (HAN) Bridges Meristem and Organ Primordia Boundaries through PINHEAD, JAGGED, BLADE-ON-PETIOLE2 and CYTOKININ OXIDASE 3 during Flower Development in Arabidopsis.
    PLoS Genet., 2015. 11(9): p. e1005479
    [PMID:26390296]